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Among these, Efpeglenatide injection is a cAMP-biased GLP-1 receptor agonist, which was approved in China in January 2026 for blood glucose control in adult patients with type 2 diabetes
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Clinical Profile of Exenatide To understand subsequent innovations, it’s helpful to summarize exenatide’s clinical profile (as the first GLP-1 RA): Efficacy: In trials, twice-daily exenatide (10 µg BID) typically reduced HbA₁c by approximately 0.8%–1.0% more than placebo by 30 weeks ( [61] ) ( [103] )
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