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Conclusions Gymnema sylvestre has several clinical trials supporting its potential as a supplement for improving glucose control , optimizing some metabolic parameters , and, acutely, reducing the craving and consumption of sweet foods
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However, reduced excitability of K cells has not been experimentally demonstrated and a recent report demonstrated fructose-stimulated GIP secretion in mice with streptozotocin-induced diabetes which seemed, however, also not dependent on K ATP -channel closure [Seino et al